CALCULATIONS
| Adjusted Calcium (mg/dL) | Total Calcium + 0.8 x (4.0-Albumin) |
| Included In | Adjusted Calcium Phosphorus Product |
| Comprehensive Metabolic Panel | |
| Comprehensive Metabolic Panel w/Phosphorus | |
| Note | Calculation provided only when Albumin is <4.0 g/dL |
| Adjusted Calcium Phosphorus Product (mg²/dL²) | (Total Calcium (mg/dL) + 0.8 x (4.0-Albumin (g/dL)) x Phosphorus |
| Included In | Adjusted Calcium Phosphorus Product |
| Comprehensive Metabolic Panel w/Phosphorus | |
| Note | Calculation provided only when Albumin is <4.0 g/dL |
| A/G Ratio | Albumin/Globulin |
| Included In | Comprehensive Metabolic Panel |
| Comprehensive Metabolic Panel w/Phosphorus | |
| Anion Gap (mEq/L) | Sodium – (Chloride + CO2) |
| Included In | Basic Metabolic Panel |
| Comprehensive Metabolic Panel | |
| Comprehensive Metabolic Panel w/ Phosphorus | |
| Electrolytes | |
| Renal Function Panel | |
| Calcium Phosphorus Product (mg2/dL2) | Total Calcium x Phosphorus |
| Included In | Calcium Phosphorus Product |
| Adjusted Calcium Phosphorus Product | |
| Comprehensive Metabolic Panel w/Phosphorus | |
| eGFR (mL/min/1.73 m²) | 175 x (Scr)-1.154 x (age)-0.203 x (0.742 if female) x (1.210 if African American) |
| Included In | eGFR (CKD, Non Dialysis) |
| Note | Estimated GFR (eGFR) using IDMS-Traceable Modification of Diet in Renal Disease (MDRD) |
| Globulin (g/dL) | Total Protein–Albumin |
| Included In | Comprehensive Metabolic Panel |
| Comprehensive Metabolic Panel w/Phosphorus | |
| Hemoglobin x 3 (g/dL) | Hemoglobin x 3 |
| Included In | Complete Blood Count (CBC) & Differential |
| Complete Blood Count (CBC) & Differential w/Reticulocytes | |
| Hemoglobin | |
| Hemoglobin & Hematocrit (H&H) | |
| Hemogram (Complete Blood Count w/o Differential) | |
| Iron Status w/Iron & Transferrin Panel | |
| Total Iron Binding Capacity (TIBC) (µg/dL) | Transferrin x 1.4 |
| % Transferrin Saturation | (Iron/(Transferrin x 1.4)) x 100 |
| Lipid Panel (Coronary Risk Profile) | |
| Cholesterol/HDL Ratio | Cholesterol/HDL |
| Low Density Lipoprotein (mg/dL) | Cholesterol – (Very Low Density Lipoprotein + HDL) |
| Very Low Density Lipoprotein (mg/dL) | Triglycerides/5 |
| Note | Only provided if Triglyceride is <400 mg/dL |
| Prothrombin Time (Protime) | |
| International Normalized Ratio (INR) | (PT Ratio)ISI |
| PT Ratio = (Patient PT/Mean Normal PT)ISI | |
| Mean Normal PT = Geometric Mean | |
| ISI = International Sensitivity Index | |
| Recirculation Study | |
| % Recirculation | (Systemic BUN – Arterial BUN)/(Systemic BUN – Venous BUN) x 100 |
| HEMODIALYSIS CALCULATIONS | |
| Kt/V Equilibrated (eqKt/V) | (0.924 x lnKt/V) – ((0.395 x lnKt/V) / (Min / 60)) + 0.056 |
| Included In | Kt/V Standard, URR |
| Kt/V Standard, Natural Log, URR | |
| Note | Leypoldt Formula |
| For patient dialyzing 2 or 4-6 times per week | |
| For Kt/V Standard calculation purposes only, not reported | |
| Kt/V Jindal | (0.04 x ((Pre BUN – Post BUN) / Pre BUN x 100) – 1.2) |
| Included In | Kt/V Jindal (Not K/DOQI Recommended) |
| Note | Jindal Formula |
| The HD Adequacy Work Group feels this formula should not be used to measure delivered dose of Hemodialysis. (K/DOQI Clinical Practice Guidelines for Hemodialysis Adequacy: Update 2000, Guideline 2) | |
| Kt/V Natural Log (lnKt/V) | (-Ln((Post BUN/Pre BUN) - (0.008 x Treatment Time in mins/60)) + ((4-(3.5 x (Post BUN/Pre BUN)) x (Pre WT-Post WT)/Post WT)) |
| Included In | Kt/V Natural Log, URR |
| Kt/V Natural Log, URR, nPNA | |
| Kt/V Standard, Natural Log, URR | |
| Note | Daugirdas II Formula |
| The K/DOQI recommendations are: Prescribed dose of hemodialysis: Kt/V of 1.3 | |
| Delivered dose of hemodialysis: Kt/V >1.2 | |
| Kt/V Standard (stdKt/V) | 168 x (1-exp(-eqKt/V)) / (Min/60)) / ((1-exp(-eqKt/V)) / eqKt/V + (168/Number of Treatment/(Min/60)) -1) |
| Included In | Kt/V Standard, URR |
| Kt/V Standard, Natural Log, URR | |
| Note | Leypoldt Formula |
| For patient dialyzing 2 or 4-6 times per week | |
| nPNA, Hemodialysis | 1. Treatment #1: Beginning of week PNA (PCR) = Pre BUN /(36.3 + 5.48 x Kt/V Natural Log + 53.5/ Kt/V Natural Log) + 0.168 |
| 2. Treatment #2: Midweek PNA (PCR) = Pre BUN /(25.8 + 1.15 x Kt/V Natural Log + 56.4/ Kt/V Natural Log) + 0.168 | |
| 3. Treatment #3: End of week PNA (PCR) = Pre BUN /(16.3 + 4.3 x Kt/V Natural Log + 56.6/ Kt/V Natural Log) + 0.168 | |
| Included In | Kt/V Natural Log, URR, nPNA |
| Note | nPNA calculation is only applicable to patients on thrice-weekly dialysis without significant residual function. nPNA calculated from Kt/V without formal kinetic modeling according to Depner T and Daugirdas J:JASN 1996:7:780-785. |
| Urea Reduction Ratio (%) | (1 – (Post BUN/Pre BUN)) x 100 |
| Included In | Kt/V Jindal (Not K/DOQI Recommended) |
| Kt/V Natural Log, URR | |
| Kt/V Natural Log, URR, nPNA | |
| Kt/V Standard, Natural Log, URR | |
| Kt/V Standard, URR | |
| Ultrafiltration Rate (UFR) (mL/kg/hr) | ((pre-weight – post-weight) x 1000)/ (delivered time in mins/60)/ post-weight in kg)) |
| Included In | Kt/V Natural Log, URR |
| Kt/V Natural Log, URR, nPNA | |
| Kt/V Standard, Natural Log, URR | |
| Kt/V Standard, URR |
| PD ADEQUACY CALCULATIONS | |
| Weekly Total Kt/V | Weekly Residual Kt/V + Weekly Dialysate Kt/V |
| Weekly Residual Kt/V | ((Urine Urea Nitrogen/BUN) x (Urine Volume (mL)/Urine Collection Time (min)) x 10.08) / VSA |
| Note | Calculated if urine sample provided |
| Weekly Dialysate Kt/V | ((Dialysate Urea Nitrogen/BUN) x (24 hour Dialysate Drain Volume (mL)/1000) x 7) / VSA |
| Weekly Total CrCl | Weekly Residual GFR + Weekly Dialysate Creatinine Clearance |
| (L/wk/1.73 m²) | |
| Weekly Residual GFR | Arithmetic Mean of Weekly Urea Clearance and Weekly Creatinine Clearance |
| (L/wk/1.73 m²) | ((Urine Urea Nitrogen/BUN) x (Urine Volume (mL)/Urine Collection Time (min) x 10.08) + (Urine Creatinine/Plasma Creatinine x Urine Volume (mL)/Urine Collection Time (min) x 10.08))/2 x 1.73/BSA |
| Weekly Dialysate CrCl | (Dialysate Corrected Creatinine/Plasma Creatinine) x (24 hour Dialysate Drain Volume (mL)/1000) x 7 x 1.73/BSA |
| (L/wk/1.73 m²) | |
| Weekly Residual CrCl | (Urine Creatinine/Blood Creatinine) x (Urine Volume (mL)/Urine Collection Time (min)) x (1.73/BSA) x 10.08 |
| (L/wk/1.73 m²) | |
| Creatinine Clearance | (Urine Creatinine/Blood Creatinine) x (Urine Volume (mL)/Urine Collection Time (min)) x (1.73/BSA) |
| (mL/min/1.73m2) | |
| Corrected Creatinine, 24 Hour (mg/dL) | Creatinine at 24 Hour Dwell – (Glucose at 24 Hour Dwell x 0.00010386) |
| nPNA, Peritoneal Dialysis (g/kg/day) | (10.76 x ((0.69 x UNA) + 1.46)) / (VSA/0.58) |
| Protein Nitrogen Appearance (PNA) (g/day) | 10.76 x ((0.69x UNA) + 1.46) |
| UNA (g/day) | (24 Hour Drain Volume (mL) x 24 Hour Urea Dialysate)/100000 + (Urine Volume (mL) x Urine Urea Nitrogen)/100000) x (1440/Total Urine Collection Time (min)) |
| Note | For PNA calculation purposes only, not reported |
| Body Surface Area (BSA) | Adult (≥16 years) uses DuBois and DuBois formula |
| BSA (m²) = 0.007184 x Wt^0.425 x Ht^0.725 | |
| Pediatric (< 16 years) uses Haycock formula | |
| BSA (m²) = 0.024265 x Wt^0.5378 x Ht^0.3964 | |
| where weight (Wt) is in kilograms and height (Ht) is in centimeters | |
| Volume (V) from Surface Area (Liters) | Adult (≥16 years) uses Hume and Weyers formula |
| Male: V= -14.012934 + 0.296785 x Wt + 0.194786 x Ht | |
| Female: V = -35.270121 + 0.183809 x Wt + 0.344547 x Ht | |
| Pediatric (<16 years) uses Friis-Hansen formula | |
| V = 0.135 x Wt^0.666 x Ht^0.535 | |
| where weight (Wt) is in kilograms and height (Ht) is in centimeters |
| Peritoneal Equilibration Test (PET) Fast | |
| Corrected Creatinine, 4 Hour (mg/dL) | Creatinine at 4 Hour Dwell – (Glucose at 4 Hour Dwell x 0.00010386) |
| Corrected Creatinine D/P, 4 Hour | Corrected Creatinine at 4 Hour Dwell/Plasma Creatinine |
| Peritoneal Equilibration Test (PET) Standard | |
| Corrected Creatinine, 0 Hour, 2 Hour, 4 Hour (mg/dL) | Creatinine at 0 or 2 or 4 Hour Dwell – (Glucose at 0 or 2 or 4 Hour Dwell x 0.00010386) |
| Corrected Creatinine D/P, 0 Hour | Corrected Creatinine at 0 Hour Dwell/Plasma Creatinine |
| Corrected Creatinine D/P, 2 Hour | Corrected Creatinine at 2 Hour Dwell/Plasma Creatinine |
| Corrected Creatinine D/P, 4 Hour | Corrected Creatinine at 4 Hour Dwell/Plasma Creatinine |
| Glucose D/D0, 2 Hour | Glucose at 2 Hour Dwell/Glucose at 0 Hour Dwell |
| Glucose D/D0, 4 Hour | Glucose at 4 Hour Dwell/Glucose at 0 Hour Dwell |
| Urea D/P, 0 Hour | Urea at 0 Hour Dwell/Plasma Urea |
| Urea D/P, 2 Hour | Urea at 2 Hour Dwell/Plasma Urea |
| Urea D/P, 4 Hour | Urea at 4 Hour Dwell/Plasma Urea |
| Peritoneal Equilibration Test (PET) Modified | |
| Corrected Creatinine, 0 Hour, 1 Hour, 2 Hour, 4 Hour (mg/dL) | Creatinine at 0 or 1 or 2 or 4 Hour Dwell – (Glucose at 0 or 1 or 2 or 4 Hour Dwell x 0.00010386) |
| Corrected Creatinine D/P, 4 Hour | Corrected Creatinine at 4 Hour Dwell/Plasma Creatinine |
| Sodium D/P, 0 Hour | Sodium at 0 Hour Dwell / Plasma Sodium |
| Sodium D/P, 1 Hour | Sodium at 1 Hour Dwell / Plasma Sodium |
| Sodium D/P, 2 Hour | Sodium at 2 Hour Dwell / Plasma Sodium |
| Sodium D/P, 4 Hour | Sodium at 4 Hour Dwell / Plasma Sodium |
| Fluid, 24-Hour Dwell | |
| Corrected Creatinine, 24 Hour (mg/dL) | Creatinine at 24 Hour Dwell – (Glucose at 24 Hour Dwell x 0.00010386) |
| Fluid, Overnight Dwell | |
| Corrected Creatinine, Overnight (mg/dL) | Creatinine Overnight Dwell – (Glucose Overnight Dwell x 0.00010386) |
| 24 Hour Urine Creatinine Clearance (Residual Renal Creatinine Clearance) | |
| Creatinine Clearance (mL/min/1.73m2) | (Urine Creatinine/Blood Creatinine) x (Urine Volume (mL)/Urine Collection Time (min)) x (1.73/BSA) |
| Body Surface Area (BSA) | Adult (≥16 years) uses DuBois and DuBois formula |
| BSA (m²) = 0.007184 x Wt^0.425 x Ht^0.725 | |
| Pediatric (< 16 years) uses Haycock formula | |
| BSA (m²) = 0.024265 x Wt^0.5378 x Ht^0.3964 | |
| where weight (Wt) is in kilograms and height (Ht) is in centimeters | |
| Residual Urea Clearance, KrU – for Hemodialysis only | |
| KrU (mL/min) | (Urine Urea Nitrogen x Urine Volume (mL)) / (Blood BUN x 0.9 x Total Urine Collection Time (min)) |
| Kt/V Residual | (Urine Urea Nitrogen/Blood BUN) x (Urine Volume (mL)/ Urine Collection Time (min)) x (10.08/VSA) |
| Volume (V) from Surface Area (Liters) | Adult (≥16 years) uses Hume and Weyers formula |
| Male: V= -14.012934 + 0.296785 x Wt + 0.194786 x Ht | |
| Female: V = -35.270121 + 0.183809 x Wt + 0.344547 x Ht | |
| Pediatric (<16 years) uses Friis-Hansen formula | |
| V = 0.135 x Wt^0.6660.666 x Ht^0.535 | |
| where weight (Wt) is in kilograms and height (Ht) is in centimeters | |
| 24 Hour Urine Creatinine | |
| Urine Creatinine, 24 Hour (g/24 hr) | ((Urine Creatinine in mg/dL x Urine Volume in mL)/100) x (1440 / Total Urine Collection Time in min) |
| 24 Hour Urine Urea Nitrogen | |
| Urine Urea Nitrogen, 24 Hour (g/24 hr) | ((Urine Urea Nitrogen in mg/dL/100) x (Urine Volume in mL/(Total Urine Collection Time in mins/1440)))/1000 |
| 24 Hour Urine Total Protein with Creatinine | |
| Urine Protein, 24 Hour (g/24 hr) | (Urine Total Protein/100) x ((Urine Volume in mL)/(Total Urine Collection Time in mins/1440)) |
| Urine Total Protein/ Creatinine Ratio, 24 Hour (mg/g creat) | ((Urine Total Protein/100) x ((Urine Volume in mL)/(Total Urine Collection Time in mins/1440)))/(((Urine Creatinine/100) x (Urine Volume in mL/(Total Urine Collection Time in mins /1440)))/1000) |
| Urine Creatinine, 24 Hour (g/24 hr) | ((Urine Creatinine/100) x (Urine Volume in mL/(Total Urine Collection Time in mins/1440)))/1000 |
| Random Urine Total Protein with Creatinine | |
| Urine Total Protein/ Creatinine Ratio (mg/g creat) | (Total Protein, Random Urine/Creatinine, Random Urine) x 1000 |
| Gotch PD QA | |
| Corrected Creatinine, PD QA (mg/dL) | (Corrected Creatinine, PD QA – Glucose PD QA x 0.00010386) |
| Total Protein, PD QA (g/dL) | Total Protein, PD QA / 1000 |
| Gotch PD Exchange 1 | |
| Corrected Creatinine, PD Exchange 1 (mg/dL) | (Corrected Creatinine, PD Exchange 1 – Glucose PD Exchange 1 x 0.00010386) |
| Total Protein, PD Exchange 1 (g/dL) | Total Protein, PD Exchange 1 / 1000 |
| Gotch PD Exchange 2 | |
| Corrected Creatinine, PD Exchange 2 (mg/dL) | (Corrected Creatinine, PD Exchange 2 – Glucose PD Exchange 2 x 0.00010386) |
| Total Protein, PD Exchange 2 (g/dL) | Total Protein, PD Exchange 2 / 1000 |
| Gotch PD Exchange 3 | |
| Corrected Creatinine, PD Exchange 3 (mg/dL) | (Corrected Creatinine, PD Exchange 3 – Glucose PD Exchange 3 x 0.00010386) |
| Total Protein, PD Exchange 3 (g/dL) | Total Protein, PD Exchange 3 / 1000 |
| Gotch PD Exchange 4 | |
| Corrected Creatinine, PD Exchange 4 (mg/dL) | (Corrected Creatinine, PD Exchange 4 – Glucose PD Exchange 4 x 0.00010386) |
| Total Protein, PD Exchange 4 (g/dL) | Total Protein, PD Exchange 4 / 1000 |
| Gotch PD Exchange 5 | |
| Corrected Creatinine, PD Exchange 5 (mg/dL) | (Corrected Creatinine, PD Exchange 5 – Glucose PD Exchange 5 x 0.00010386) |
| Total Protein, PD Exchange 5 (g/dL) | Total Protein, PD Exchange 5 / 1000 |