Tacrolimus
| Alternate Names | Prograf, FK506 | 
| Ordering Recommendation | Tacrolimus is an immunosuppressive drug believed to prevent rejection in transplant patients. Measurements may be used to optimize dosing and monitor patient adherence. | 
| Specimen | Whole Blood | 
| Container Type | Lavender Top Tube 
 | 
| Methodology | Homogenous Enzyme Immunoassay | 
| Reference Range | Not Established; No definitive therapeutic or toxic ranges have been established. Optimal blood drug levels are influenced by type of transplant, patient response, time post-transplant, co-administration of other drugs and drug formulation. The following trough range is a suggested guideline: 5.0-20.0 ng/mL | 
| Stability | 7 days | 
| Transport Temperature | Refrigerate 2°-8° C | 
| Instructions | A trough sample (12 hours after the last dose) is recommended for measurement of tacrolimus. | 
| Days Performed | Tuesday, Friday | 
| Report Available | 1-4 days | 
| NY State Available | Yes | 
| LOINC | 74096-9 | 
| CPT Code | 80197 | 

