Hemoglobin A1C
| Alternate Names | Glycohemoglobin, A1c, HA1c, HbA1c, Hgb A1c |
| Ordering Recommendation | Use to diagnose and monitor diabetes mellitus and monitor prediabetes. Interpretative ranges are based on ADA guidelines.
For patients with known hemoglobin variants without hemoglobin A, the preferred test for monitoring long-term glycemic control is Fructosamine. |
| Specimen | EDTA Whole Blood |
| Container Type | Lavender Top Tube
|
| Methodology | Enzymatic* |
| Reference Range | Normal: <5.7% Prediabetes: 5.7-6.4% Diabetes: >6.4% Diabetic Glucose Control Evaluation: |
| Stability | 7 days |
| Transport Temp | Refrigerate 2°- 8°C |
| Instructions | This assay provides accurate results for hemoglobin A1c in the presence of hemoglobin A and the most common heterozygous hemoglobin variants (HbS, HbC, HbD, HbE, and HbF <30%). In patients with known homozygous and double heterozygous hemoglobin variants, hemoglobin A is absent. In such situations, measurement of long-term glycemic control should be monitored with an alternative assay, such as Fructosamine [1].
*If unable to obtain results via the enzymatic method, testing will be performed using ion-exchange high-performance liquid chromatography (HPLC). |
| Days Performed | Daily |
| Report Available | 1 – 3 days |
| NY State Available | Yes |
| LOINC Code | 17856-6 |
| CPT Code | 83036 |
| Reference | 1. Lee JE. Alternative biomarkers for assessing glycemic control in diabetes: fructosamine, glycated albumin, and 1,5-anhydroglucitol. Ann Pediatr Endocrinol Metab. 2015 |
